COVID-19 Vaccines Reduce, Not Increase, Risk of Stillbirth

10.11.2022, 4:30, Разное
  Подписаться на Telegram-канал
  Подписаться в Google News
  Поддержать в Patreon

SciCheck Digest

There is no link between COVID-19 vaccination and an increased risk of stillbirth, despite such claims online. In fact, vaccination has been shown in multiple studies to reduce the risk of stillbirth by protecting pregnant people and their babies from the coronavirus.

How do we know vaccines are safe?

How do we know vaccines are safe?

No vaccine or medical product is 100% safe, but the safety of vaccines is ensured via rigorous testing in clinical trials prior to authorization or approval, followed by continued safety monitoring once the vaccine is rolled out to the public to detect potential rare side effects. In addition, the Food and Drug Administration inspects vaccine production facilities and reviews manufacturing protocols to make sure vaccine doses are of high-quality and free of contaminants.

One key vaccine safety surveillance program is the Vaccine Adverse Event Reporting System, or VAERS, which is an early warning system run by the Centers for Disease Control and Prevention and FDA. As its website explains, VAERS “is not designed to detect if a vaccine caused an adverse event, but it can identify unusual or unexpected patterns of reporting that might indicate possible safety problems requiring a closer look.”

Anyone can submit a report to VAERS for any health problem that occurs after an immunization. There is no screening or vetting of the report and no attempt to determine if the vaccine was responsible for the problem. The information is still valuable because it’s a way of being quickly alerted to a potential safety issue with a vaccine, which can then be followed-up by government scientists.

Another monitoring system is the CDC’s Vaccine Safety Datalink, which uses electronic health data from nine health care organizations in the U.S. to identify adverse events related to vaccination in near real time.

In the case of the COVID-19 vaccines, randomized controlled trials involving tens of thousands of people, which were reviewed by multiple groups of experts, revealed no serious safety issues and showed that the benefits outweigh the risks.

The CDC and FDA vaccine safety monitoring systems, which were expanded for the COVID-19 vaccines and also include a new smartphone-based reporting tool called v-safe, have subsequently identified only a few, very rare adverse events. 

For more, see “How safe are the vaccines?”

Link to this

Full Story

Numerous studies evaluating the safety of the COVID-19 vaccines in pregnant people have found no increased risk of stillbirth among those who have been vaccinated. Far from demonstrating a safety hazard, vaccination has been shown to reduce a variety of coronavirus-related risks during pregnancy, including stillbirth.

Despite the robust safety findings, online posts have been circulating a “leaked” memo from a Fresno, California, hospital to incorrectly suggest that COVID-19 vaccination increases the risk of stillbirth.

“Leaked Hospital Email Reveals Explosion of Stillbirths Following COVID Vaccine Rollout,” reads one headline from the conspiracy theory website InfoWars, which was shared on Instagram.

The claim appears to originate with an Oct. 24 story in the Epoch Times, a far-right outlet affiliated with the Chinese spiritual movement Falun Gong. The site is frequently a source of misinformation, including on COVID-19 and vaccines.

According to the Epoch Times story, a staff member at a Fresno hospital claimed that the stillbirth rate had “skyrocketed” after the COVID-19 vaccine rollout. The employee shared an email from a managing nurse on Sept. 8 that referred to an apparent uptick in the number of “demise patients” occurring across the hospital system, including 22 demises in August, which tied the record in July 2021.

But the memo makes no mention of COVID-19 vaccination and is primarily focused on informing nursing staff how to properly handle the demise specimens. Moreover, the email never states that its figures are only for stillbirths.

Fetal death, or fetal demise, refers to death at any time in pregnancy. Deaths before 20 weeks of gestation are miscarriages, while deaths after 20 weeks (or sometimes 28 weeks) are considered stillbirths. Conflating stillbirth with fetal death erroneously exaggerates the number of stillbirths.

The public health departments of Fresno County and California also told us there has not been a significant increase in the stillbirth rate since the introduction of COVID-19 vaccines.

Citing Dr. James Thorp, a Florida gynecologist who has spread misinformation about the COVID-19 vaccines before, the Epoch Times proceeded to then falsely claim that the memo was “consistent” with other vaccine safety monitoring data in showing that the vaccines are hazardous during pregnancy. 

That’s incorrect. The memo doesn’t implicate the COVID-19 vaccines, nor does the existing evidence suggest that vaccination is unsafe for pregnant people and their fetuses. On the contrary, vaccination can protect against COVID-19, which can be particularly dangerous for pregnant people and raise the risk of pregnancy complications, including stillbirth.

COVID-19 Vaccination Can Protect Against Stillbirth

According to a regularly updated online explainer by Victoria Male, a lecturer in reproductive immunology at Imperial College London, 16 studies have assessed COVID-19 vaccination safety with respect to stillbirth, and none has found an increased risk of stillbirth following COVID-19 vaccination.

A meta-analysis reviewing some of those studies, the explainer notes, “found that COVID vaccination actually reduces the risk of stillbirth,” likely because of the risk posed by coronavirus infection. The meta-analysis, published in Nature Communications in May, found the “risk of stillbirth was significantly lower in the vaccinated cohort by 15%.”

Dr. Brenna Hughes, a maternal-fetal medicine specialist at Duke University Health System who has studied COVID-19 during pregnancy, also directed us to a study published this month in the American Journal of Obstetrics & Gynecology that found vaccinated women in Australia were about 80% less likely to experience a stillbirth compared with unvaccinated women. Hughes told us the claims in the posts were “quite false.”

Numerous studies have found that pregnant people who get infected with the coronavirus, or SARS-CoV-2, have a higher risk of stillbirth and other bad outcomes for both the mother and the baby than those who do not get infected.

A Centers for Disease Control and Prevention study of more than 1.2 million delivery hospitalizations between March 2020 and September 2021, for example, found that American women with COVID-19 had nearly double the risk of a stillbirth compared with those who did not have COVID-19. The risk was more than four times as high when the delta variant was dominant.

A meta-analysis of 111 studies, which included more than 42,000 pregnant women, found that COVID-19 significantly increased the risk of premature delivery, preeclampsia, neonatal death, maternal death and stillbirth. The risk of stillbirth among those with COVID-19 was nearly 2.4 times higher than for women without COVID-19.

Research suggests that among women with COVID-19, it’s infection of the placenta, or what’s called SARS-CoV-2 placentitis, that increases the risk of stillbirth. The placenta is a temporary organ that develops during pregnancy that delivers nutrients and oxygen to the fetus, among other functions.

It’s relatively rare, but as a review published in October in the American Journal of Obstetrics & Gynecology explains, the coronavirus can destroy more than 75% of the placenta, preventing it from providing oxygen and killing the fetus. Some autopsies of stillbirths born to mothers infected with SARS-CoV-2 have shown signs of asphyxia. In most cases, the fetus isn’t directly infected with the virus.

Unlike with many aspects of COVID-19, there doesn’t appear to be a link between COVID-19 severity and stillbirth. Some reported cases of stillbirths with SARS-CoV-2 placentitis have even occurred in pregnant people who were asymptomatic.

Even so, it’s striking that among the SARS-CoV-2 stillbirth cases described in the literature, none has been in a vaccinated mother.

“It seems beyond coincidence that in the multiple reports of SARS-CoV-2 placentitis associated with stillbirths and neonatal deaths, none of the mothers had received COVID-19 vaccinations,” the review notes. “In addition, although not constituting proof, the authors are not aware either personally, via collegial networks, or in the published literature of any cases of SARS-CoV-2 placentitis causing stillbirths among pregnant women who received the COVID-19 vaccine.”

The authors of the review suspect that vaccination likely protects against stillbirth by preventing SARS-CoV-2 from getting into the bloodstream, which is probably how the virus reaches the placenta.

Consistent with the notion that vaccination is effective in reducing the risk of COVID-19-related stillbirth, preliminary v-safe COVID-19 Pregnancy Registry data presented to the CDC’s vaccine advisory committee last month found that pregnant people who were fully vaccinated and contracted the coronavirus did not have a higher risk of stillbirth than their peers who didn’t get infected.

To be clear, the chances of a pregnant person having a stillbirth, even if infected with the coronavirus, is still quite low. According to the CDC, there’s about 1 stillbirth in every 175 births, which would mean it happens less than 0.6% of the time. Doubling or tripling this risk would mean that the risk would still be below 2%.

But if someone is concerned about stillbirth — not to mention all the other maternal and fetal complications of COVID-19 — the evidence shows COVID-19 vaccination would be a good idea, not a bad one, as the posts online suggest.

Fresno Claim

Beyond the overwhelming evidence that COVID-19 vaccination does not cause stillbirths, the details about the alleged increase in Fresno stillbirths also don’t add up.

We reached out to multiple birthing hospitals in the city and were able to identify the hospital system responsible for the memo that was shared with the Epoch Times as Community Medical Centers.

In a statement, the hospital said that the email was about hospital policy, did not include any reference to COVID-19 vaccination — and was not limited to just stillbirths.

“There are a number of reasons for a fetal demise and it can go unexplained in some cases,” Sarah Putman, the director of women & newborn health at Community Regional Medical Center, said. “This was an internal memo from a clinical staff member to others in the unit reminding them to adhere to hospital policy, and thanking them for the time and attention they have provided to patients. The memo writer made a personal observation about all pregnancy losses in the memo that was secondary to reinforcing hospital policies and procedures with staff. There was no mention by that staff member about a cause for this observation, and neither COVID-19 nor vaccines were mentioned.”

The email specifically mentions “demise patients” who died before 20 weeks, which would be miscarriages, not stillbirths. Setting aside the fact that the 22 demises in August mentioned in the memo is not an official figure to start — and is only for a short period of time at a single hospital system — it’s incorrect to calculate a stillbirth rate from the number, as the physician quoted in the Epoch Times article did. 

Scientists have much better and more robust data to evaluate whether vaccination increases the risk of stillbirth, and the evidence is clear that it does not.

The claim is also predicated on the idea that there has been a rise in stillbirths over the last two years. While it’s possible that could be the case for the one hospital system — Imperial College London’s Male said that could be due to several reasons, such as an outbreak of certain infectious diseases, changes in prenatal care or random chance — there is no sign of any kind of widespread increase in stillbirths in the area.

The California Department of Public Health told us that as of November 2022, there had been “no significant increase in California stillbirth rates since the introduction of COVID-19 vaccines, and no stillbirth certificate has mentioned ‘COVID-19 Vaccination.’”

An epidemiologist with the Fresno County Department of Public Health told us that was also the case for Fresno, adding that the department has a fetal and infant mortality review team, which has not reviewed a concern about the vaccines.

Given that COVID-19 increases the risk of stillbirth, it’s reasonable to think there might have been an increase in stillbirth rates over the past couple of years. The most recent national data only go up to 2020, and the rate of 5.74 deaths per 1,000 births was not significantly different from the rate of 5.70 in 2019. This fact was mentioned by Thorp in the Epoch Times article, although he cherry-picked a comparison with 2018, when the rate was slightly higher.

Time will tell what the national statistics will look like — the CDC told us the 2021 data would be expected to be released in the summer of 2023, per the usual schedule — but whatever the stillbirth rate is, it won’t mean that COVID-19 isn’t a risk to pregnant people.

Male explained that because stillbirth is quite rare, the additional stillbirths due to COVID-19 might not make that big of an impact on the national numbers. She told us, for example, that in the U.K., there were only 77 COVID-19 stillbirths up through October 2021 — which wasn’t a lot relative to the annual baseline of about 2,500. And because the stillbirth rate in the U.S. is higher than in the U.K., she said, “COVID stillbirths are likely to make even less of an impact” in America.

Again, the data are already clear that COVID-19 increases the risk of stillbirth and vaccination can reduce that risk.




Смотреть комментарииКомментариев нет


Добавить комментарий

Имя обязательно

Нажимая на кнопку "Отправить", я соглашаюсь c политикой обработки персональных данных. Комментарий c активными интернет-ссылками (http / www) автоматически помечается как spam

Политика конфиденциальности - GDPR

Карта сайта →

По вопросам информационного сотрудничества, размещения рекламы и публикации объявлений пишите на адрес: [email protected]

Поддержать проект:
ЮMoney - 410011013132383
WebMoney – Z399334682366, E296477880853, X100503068090

Выборы президентов России, США, Украины и Олимпиада в Париже

18+ © 2021-2024 Ryb.Ru

Яндекс.Метрика